The proposed system generates non-contact ECG signals with distinguishable R-peaks at the limb-electrode capacitance above 8.5 pF and maximum through-thickness of the non-conductive layer of 0.4 mm for heart rate assessment. The method utilizes the capacitive coupling technique to detect cardiac signals in the awake rats (R-wave amplitude of only 0.2 mV) through a non-conductive layer. ![]() This study aims to develop a non-contact ECG system to promote the laboratory animal ECG measurement for biomedical research. However, the non-contact capacitive ECG sensing approach for small laboratory animals has not been extensively investigated. Most studies used the galvanic contact between animal limb and electrode sensing surface to record cardiac signals from small animals. However, such an invasive measurement could cause inconvenience due to cumbersome animal preparation, and the anesthetics are likely to interfere with the autonomic regulation of cardiac rhythm. The subcutaneous ECG is a common approach to record rat heart rhythm using implanted needle electrodes to sense the rat ECG signals with the animal under deep anesthesia. Rat electrocardiography (ECG) is frequently used in biomedical research as models for exploring heart function in a wide variety of experimental conditions.
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